I have a 2x SCSI CD-ROM in a custom case that I bought from an Amiga supplier. Can I upgrade the drive by replacing it with a faster unit such as a 20x or do I have to buy abandon this and buy a new drive?

As long as the drive is SCSI compatible to connect to your SCSI interface inside the CD-ROM unit you should be able to use one. Just replace the old drive with the new one, checking all jumper settings for SCSI ID and termination settings.

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